Ref.: MpoBi22-006

A novel bionanocomposite film using alginate and functionalized montmorillonite: impact of mechanical and antibacterial properties

Apresentador: JULIANE PAULA DE LIMA PEREIRA

Autores (Instituição): PEREIRA, J.P.(UNIVERSIDADE FEDERAL RURAL DE PERNAMBUCO); de Souza, L.V.(UNIVERSIDADE FEDERAL RURAL DE PERNAMBUCO); Lins, A.d.(UNIVERSIDADE FEDERAL RURAL DE PERNAMBUCO); SILVA, L.B.(UNIVERSIDADE FEDERAL RURAL DE PERNAMBUCO); Melo, A.N.(Universidade Federal Rural de Pernambuco); TRIGUEIRO, P.(UNIVERSIDADE FEDERAL RURAL DE PERNAMBUCO); da Silva, D.v.(UNIVERSIDADE FEDERAL RURAL DE PERNAMBUCO); da Silva, B.V.(UNIVERSIDADE FEDERAL RURAL DE PERNAMBUCO); Andrade, D.A.(Universidade Federal de Campina Grande); Peña, R.R.(Universidade Federal Rural de Pernambuco);

Resumo:
Natural polymers are a group of materials that are gaining increasing attention due to their diverse properties. Polysaccharides like alginate are particularly noteworthy due to their high availability, biocompatibility and biodegradability. When combined with inorganic materials such as clay minerals and oxide nanoparticles, alginate can be further enhanced in its therapeutic effects, barrier properties and mechanical strength. The objective of this work was to develop and analyze a bionanocomposite made of alginate and montmorillonite that has been functionalized with cerium (Ce-montmorillonite). The film composition included 5% w/v of alginate, 30% w/w of glycerol, and 1.5% w/w of Ce-montmorillonite. The addition of clay mineral did not affect the structural properties of the film, as shown by infrared spectroscopy and X-ray diffraction analysis. However, differential scanning calorimeter analysis indicated that the melting temperature of the film increased with the addition of clay mineral. The incorporation of Ce-montmorillonite also significantly enhanced the antimicrobial activity against Escherichia coli and Staphylococcus aureus of the biocomposite film compared to the pure alginate film. Furthermore, the biocomposite film exhibited lower water vapor transmission and swelling capacity when prepared with to the pure alginate film. The presence of Ce-montmorillonite also slightly increased the strength and rigidity of the biofilm. These results suggest that the inclusion of montmorillonite functionalized with cerium in alginate-based films can improve their properties and make them suitable for use as biofilm in dressing exudative wounds.