Ref.: MpoBi02-010
Apresentador: Renata Nunes Oliveira
Autores (Instituição): Oliveira, R.N.(UNIVERSIDADE FEDERAL RURAL DO RIO DE JANEIRO); Araujo, R.d.(UNIVERSIDADE FEDERAL RURAL DO RIO DE JANEIRO); de Oliveira, L.F.(UNIVERSIDADE FEDERAL RURAL DO RIO DE JANEIRO); Middea, A.(Ccentro de Tecnologia Mineral); Lima, E.M.(EMBRAPA Agroindústria de Alimentos);
Resumo:
Infection is a serious complication that can occur in the acute period after a burn injury. The main goals of topical treatment are to promote healing, prevent wound infection and achieve fast closure possible. PVA is a hydrophilic polymer vastly studied as an electrospun matrix for drug delivery. "Dragon's blood" (DB) is a natural compound widely used in the treatment of wounds to try to prevent infection. The goal of this work was to evaluate electrospun PVA membranes loaded with dragon's blood by SEM, correlating the effect of composition on fibre diameter. Samples were successfully electrospun, although the presence of DB led to beads formation. Lower concentration PVA solutions and solutions with higher amounts of DB presented thin fibres. However, the addition of DB resulted in beads in all fibres, probably due to the fluids viscosity. Further analyses are required to access the antioxidant potential of the mats. The authors thank FAPERJ Processo SEI E-26/201.381/2021 (260532) for funding grant for this work.